iGlycoMab Stable Isotope Labeled Glycan Standard
iGlycoMab is a highly purified murine IgG2b monoclonal antibody whose glycans are labeled with the stable isotope (15N).
iGlycoMab was developed to be used as an internal standard for the quantitation of glycoprotein glycans, and is well suited as a standard for monoclonal antibodies as well as Fc-fusion therapeutics because of the similarity in glycan structure and amino acid sequence near the Fc glycosylation site.
Because iGlycoMab is a full length glycoprotein standard its use compensates for the systematic errors associated with parallel sample handling, and thus provides superior results in terms increased accuracy and precision compared to traditional methods.