Guinea Pig Interleukin 23

Mature IL23 is a heterodimeric protein consisting of the IL23a (p19) subunit and the IL12b (p40) subunit.  This proinflammatory cytokine is expressed by activated macrophages and dendritic cells.  Il23 is structurally similar to mature IL12 and shares the IL12b subunit, but IL23 is unique in its ability to activate IL17.