GlycoScientific
IgG1 UmAb1
IgG1 UmAb1
IgG antibodies are composed of two heavy chain and two light chain polypeptides that are linked by disulfide bonds. IgG1 antibodies are defined by their unique carboxy-terminal part of the heavy chain. Two types of light chains, lambda (λ) and kappa (K) are functionally identical and can be found in any of the five major classes of human antibodies. GlycoScientific offers two formulations of a human monoclonal IgG1 kappa antibody purified from protein free CHO culture. See the publications list below for successful applications of IgG1 UmAb1.
Product Details:
Biosimilar: Adalimumab
Source: CHO
Clone: Monoclonal
Isotype: Human IgG1, kappa
Target: TNFa
Known Species Reactivity: Human, Guinea Pig
Form: Dried down from PBS
Assay: ≥95% (SDS-PAGE)
Label: None
Tested Applications: MS, Western blot
Click here for sample data sheet for GS0087 PBS formulation.
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This product is intended exclusively for scientific investigation or laboratory research and is not intended for diagnostic, therapeutic, or human/animal clinical use.
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Publications
Nath, N., Godat, B., Flemming, R. et al. Sci Rep 12, 12185 (2022). https://doi.org/10.1038/s41598-022-15887-z
Nath N, Godat B, Flemming R, Urh M. J Immunol. 2021 Aug 15;207(4):1211-1221. doi: 10.4049/jimmunol.2100181. Epub 2021 Jul 26. PMID: 34312257; PMCID: PMC8358922.
Misra SK, Orlando R, Weinberger SR, Sharp JS. AAPS J. 2019 Jul 11;21(5):87. doi: 10.1208/s12248-019-0358-2. PMID: 31297623; PMCID: PMC7670911.
Tadi S, Misra SK, Sharp JS. Anal Chem. 2021 Feb 23;93(7):3510-3516. doi: 10.1021/acs.analchem.0c04872. Epub 2021 Feb 9. PMID: 33560821; PMCID: PMC7951798.