Recombinant Human IgG Standard Proteins
Immunoglobulin G antibodies are glycoproteins that make up the majority of human serum antibodies and play a major role in the humoral immune response. IgG antibodies are the most prevalent of the five human classes and can further be divided into four subclasses IgG1, IgG2, IgG3, and IgG4. Antibodies are comprised of a variable region and a constant region that shares more than 90% sequence homology between these different subclasses. Despite these similarities each IgG subclass have distinct structural features and roles in immune response. The use for antibodies in therapeutics and scientific research continues to grow. Glycoscientific provides cost effective, quality recombinant antibodies to fit your research needs.
Our quality commitment
- All our recombinant IgG standards are monoclonal, allowing for predicted structure and sequence.
- Our recombinant IgGs are produced in either Chinese Hamster Ovary (CHO) or Human Embryonic Kidney (HEK) cells, resulting in functional glycoproteins.
- Protein free culture conditions for all recombinant IgGs ensure we provide ultra purified products.
- Customization and scalability-need a standard in a certain quantity or formulation? Our team of highly trained scientists would be happy to work with you on custom orders.
Collections
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Recombinant Human IgG1 Standards
IgG antibodies are composed of two heavy chain and two light chain...
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Recombinant Human IgG2 Standards
The IgG2 subclass is the second most abundant IgG behind IgG1. IgG2s...
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Recombinant Human IgG4 Standards
IgG4 antibodies differ from the more widely studied and naturally abundant IgG1...
Did you know?
GlycoScientific offers isotopically labeled versions of IgG1 and IgG4?
Publications
Nath, N., Godat, B., Flemming, R. et al. Sci Rep 12, 12185 (2022). https://doi.org/10.1038/s41598-022-15887-z
Nath N, Godat B, Flemming R, Urh M. J Immunol. 2021 Aug 15;207(4):1211-1221. doi: 10.4049/jimmunol.2100181. Epub 2021 Jul 26. PMID: 34312257; PMCID: PMC8358922.
Misra SK, Orlando R, Weinberger SR, Sharp JS. AAPS J. 2019 Jul 11;21(5):87. doi: 10.1208/s12248-019-0358-2. PMID: 31297623; PMCID: PMC7670911.
Tadi S, Misra SK, Sharp JS. Anal Chem. 2021 Feb 23;93(7):3510-3516. doi: 10.1021/acs.analchem.0c04872. Epub 2021 Feb 9. PMID: 33560821; PMCID: PMC7951798.