Recombinant Human IgG1 Standards

IgG antibodies are composed of two heavy chain and two light chain polypeptides that are linked by disulfide bonds.  IgG1 antibodies are defined by their unique carboxy-terminal part of the heavy chain.  Two types of light chains, lambda (λ) and kappa (κ) are functionally identical and can be found in any of the five major classes of human antibodies.  GlycoScientific offers two formulations of a human monoclonal IgG1 kappa antibody purified from protein free CHO culture. 

Publications

Do I Need to Trypsin Digest Before Releasing IgG Glycans With PNGase-F 

Birx L, Popov M, Orlando R. J Biomol Tech. 2023 Mar 1:3fc1f5fe.6db6338a. doi: 10.7171/3fc1f5fe.6db6338a.

 

A homogeneous bioluminescent immunoassay for parallel characterization of binding between a panel of antibodies and a family of Fcγ receptors.         

Nath, N., Godat, B., Flemming, R. et al. Sci Rep 12, 12185 (2022). https://doi.org/10.1038/s41598-022-15887-z

Deciphering the Interaction between Neonatal Fc Receptor and Antibodies Using a Homogeneous Bioluminescent Immunoassay                                      

Nath N, Godat B, Flemming R, Urh M. J Immunol. 2021 Aug 15;207(4):1211-1221. doi: 10.4049/jimmunol.2100181. Epub 2021 Jul 26. PMID: 34312257; PMCID: PMC8358922.